Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ HMTase Inhibitor IX, MM-102
A cell-permeable peptidomimetic that prevents MLL1 (Mixed Lineage Leukemia 1) from complex assembling with WDR5 (Trp-Asp Repeat Domain 5), RbBP5 (Retinoblastoma Binding Protein 5), and ASH2L (Absent Small or Homeotic-2-Like) for enhanced H3K4 methyltransferase activity (IC50
MilliporeSigma™ Calbiochem™ InSolution™ Rho Kinase Inhibitor
The InSolution™ Rho Kinase Inhibitor controls the biological activity of Rho Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ CDC25 Phosphatase Inhibitor II, NSC 663284
The CDC25 Phosphatase Inhibitor II, NSC 663284, also referenced under CAS 383907-43-5, controls the biological activity of CDC25 Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Gö 6976
Gö 6976, CAS 136194-77-9, is a cell-permeable, reversible, and ATP-competitive inhibitor of PKC (IC50 = 7.9 nM for rat brain). Exhibits selectively for PKCα (IC50 = 2.3 nM) and βI (IC50 = 6.2 nM).
MilliporeSigma™ Calbiochem™ Cinnabarinic acid
A partial, low-potency agonist highly selective for mGlu4 receptors (EC50 > 100μM, no effect on other mGlu subtype rece
MilliporeSigma™ Calbiochem™ SIRT2 Inhibitor II, AK-1
The SIRT2 Inhibitor II, AK-1, also referenced under CAS 330461-64-8, controls the biological activity of SIRT2. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Autophagy Inducer, STF-62247
A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells both in vitro and in mice in vivo.
MilliporeSigma™ Calbiochem™ Dipeptidylpeptidase IV Inhibitor IV, K579
The Dipeptidylpeptidase IV Inhibitor IV, K579, also referenced under CAS 440100-64-1, controls the biological activity of Dipeptidylpeptidase IV. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ (5Z)-7-Oxozeaenol, Curvularia sp.
(5Z)-7-Oxozeaenol, CAS 66018-38-0, is a cell-permeable, highly potent, selective, irreversible, and ATP-competitive inhibitor of MAPKKK TAK1 activity (IC50 = 8 nM).
MilliporeSigma™ Calbiochem™ Caspase Modulator II, 1541B
Caspase Modulator II, 1541B primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ NF-kB Activation Inhibitor IV
The NF-kB Activation Inhibitor IV, also referenced under CAS 139141-12-1, controls the biological activity of NF-kB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ LFM-A13
A potent, cell-permeable, reversible, substrate competitive, and specific inhibitor of Bruton's Tyrosine Kinase (BTK; IC50 = 17.2μM for human BTK
MilliporeSigma™ Calbiochem™ SQ 22536
Cell-permeable adenylate cyclase inhibitor.
MilliporeSigma™ Calbiochem™ DNA Methyltransferase Inhibitor
The DNA Methyltransferase Inhibitor, also referenced under CAS 32675-71-1, controls the biological activity of DNA Methyltransferase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Cathepsin Inhibitor III
The Cathepsin Inhibitor III controls the biological activity of Cathepsin. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.